Peter Griffin

Peter Griffin (voiced by Seth MacFarlane) is the patriarch of the Griffin household, an Irish-American blue-collar worker. He is an immature, obese, laid-back, dim-witted, outspoken, eccentric alcoholic. Peter's jobs have included working at the Happy Go Lucky Toy Factory, working as a fisherman, and currently working at Pawtucket Brewery.


Lois Griffin

Lois Patrice Griffin (voiced by Alex Borstein) is Peter's wife and the mother of Meg, Chris, and Stewie. She is a Scots/Anglo Americanhousewife who cares for her kids and her husband, while also teaching children to play the piano. She is also very flirtatious and has slept with numerous people on the show; her past promiscuous tendencies and her hard-core recreational drug-use are often stunning but overlooked.


Meg Griffin

Megan "Meg" Griffin (voiced by Lacey Chabert in season 1, Mila Kunis from season 2-present) is the Griffins' 18-year-old child and only daughter. She is a self-conscious, unattractive teenage girl with severely low self-esteem, being portrayed as generally soft and non-rebellious. The other family members treat her with contempt, as an object of abuse, and an outcast. Peter refers to Meg as "Pig" in the episode "Peter's Two Dads". Meg often attempts to "fit in" with the popular kids but is rejected. Meg has had several love interests including Brian Griffin, Mayor West, Quagmire, and Joe Swanson.


Chris Griffin

Christopher Cross "Chris" Griffin (voiced by Seth Green) is Peter and Lois' 15-year-old child. He is obese, irresponsible, and emotionally effusive. A recurring gag is that an evil monkey lives in his closet which he finds out is not evil in the episode "Hannah Banana". He tries fitting in with his peers, but fails due to his social awkwardness.


Stewie Griffin

Stewart Gilligan "Stewie" Griffin (voiced by Seth MacFarlane) is the Griffins' one-year-old child, but often behaves in adult ways, such as speaking in an upper-class British accent. He is a child genius who frequently aspired to murder his mother Lois and take over the world but has since mellowed out considerably. He built a time machine with which he and Brian have traveled through time.


Brian Griffin

Brian Griffin (voiced by Seth MacFarlane) is the family's anthropomorphic talking dog and the best friend of both Peter and Stewie. He and Stewie are often at the center of the show's most critically acclaimed episodes, most notably the "Road to..." episodes, where he and Stewie go on road-trips together. Brian is portrayed as an intellectual who often serves as the family's voice of reason, pointing out how ridiculous Peter's ideas are. He is not-so-secretly in love with Lois and is an unsuccessful, unemployed writer.